Changes in fibrinogen availability and utilization in an animal model of traumatic coagulopathy

Table 4 Coagulation analyses by RoTEM converted to ratios of baseline values

			Base line	0 minutes	30 minutes	60 minutes
ExTEM	CT	TS	1.0 (0.0)	1.18 (0.49)	1.0 (0.58)	0.77 (0.27)
		T	1.0 (0.0)	1.16 (0.29)	1.02 (0.49)	0.86 (0.26)
		S	1.0 (0.0)		1.12 (0.27)	1.04 (0.28)
		C	1.0 (0.0)		0.79 (0.43)	0.91 (0.32)
	MCF	TS	1.0 (0.0)	1.0 (0.03)	0.97 (0.02)*	0.98 (0.02) †
		T	1.0 (0.0)	1.0 (0.01)	0.95 (0.10)	0.97 (0.02)
		S	1.0 (0.0)		0.95 (0.03)	0.95 (0.02)*†
		C	1.0 (0.0)		1.02 (0.01)	1.01 (0.01)
FibTEM	CT	TS	1.0 (0.0)	0.91 (0.32)	0.64 (0.29)*†	0.66 (0.15)*†
		T	1.0 (0.0)	0.95 (0.63)	1.08 (0.67)	0.97 (0.55)
		S	1.0 (0.0)		1.14 (0.30)†	0.91 (0.11)†
		C	1.0 (0.0)		0.79 (0.43)	0.91 (0.32)
	MCF	TS	1.0 (0.0)	1.19 (0.30)	1.89 (0.81)*†	1.59 (0.39)*†
		T	1.0 (0.0)	1.45 (0.61)	0.93 (0.49)	1.15 (0.32)
		S	1.0 (0.0)		0.88 (0.07)*†	0.93 (0.13)†
		C	1.0 (0.0)		1.01 (0.16)	0.98 (0.09)

TS Trauma Shock group, T Trauma group, S Shock group, C Control group, CT Clotting time, MCF maximum clot firmness, Values are given as mean ratios of baseline values (SD).
* indicates significant change from baseline measured by paired t-test.
† indicates significant difference between TS and S groups by two-sample t-test.

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