Effects of red blood cell transfusion on hemodynamic parameters: a prospective study in intensive care unit patients

Table 3 Effects of red blood cell transfusion on hemodynamic variables

Parameter	Before RBC transfusion	After RBC transfusion	p-value compared with baseline	2 h after RBC transfusion	p-value compared with baseline
Basic hemodynamic parameters
Heart rate, bpm	95 ± 14	91 ± 16	0.007	90 ± 16	0.012
Systolic blood pressure, mmHg	130 (114-150)	136 (126-150)	0.001	131 (117-144)	0.852
Diastolic blood pressure, mmHg	57 (52-65)	63 (60-69)	<0.001	60 (55-67)	0.102
MAP, mmHg	78 (74-93)	87 (84-97)	<0.001	84 (77-93)	0.176
Cardiac preload
CVP, mmHg	16 ± 7	17 ± 7	0.048	16 ± 7	0.514
GEDVI, mL/m²	882 ± 238	869 ± 228	0.304	874 ± 223	0.626
Cardiac function
CO, L/min	9.42 ± 2.75	8.89 ± 3.06	0.020	8.70 ± 2.75	0.005
CI, L/min/m²	4.82 ± 1.21	4.53 ± 1.36	0.016	4.45 ± 1.28	0.004
SV, mL	100 ± 28	99 ± 30	0.512	98 ± 30	0.487
CPI, W/m²	0.89 ± 0.28	0.91 ± 0.27	0.403	0.85 ± 0.28	0.268
dPmax, mmHg/s	1394 (1136-1726)	1414 (1200-1677)	0.851	1287 (1056-1662)	0.245
Vascular resistance
SVRI, dynscm^-5*m²	1103 (902-1422)	1212 (1028-1856)	0.001	1193 (951-1612)	0.010
Pulmonary hydration and permeability
EVLWI, mL/kg	11 (9-14)	10 (9-14)	0.283	10 (8-13)	0.286
PVPI	1.7 (1.4-2.5)	1.8 (1.5-2.4)	0.243	1.7 (1.4-2.4)	0.992

MAP mean arterial pressure, CVP central venous pressure, GEDVI global end-diastolic volume index, CI cardiac index, CO cardiac output, SV stroke volume, CPI cardiac power index, dPmax index of left ventricular contractility, SVRI systemic vascular resistance index, EVLWI extravascular lung water index, PVPI pulmonary vascular permeability index. Data are presented as mean ± standard deviation (normally distributed data) or median and 25%-75% percentile range (not normally distributed data).