Figure 1

Free oscillation rheometry. The ReoRox G2 rheometer (upper left corner) and a schematic picture of its free oscillation sample cup (upper right corner). The magnet turns the sample cup around the torsion wire. Upon release, an oscillatory movement starts which is recorded by an optical detector. The change in damping generates a viscosity curve (dashed line) and the change in frequency generates an elasticity curve (full line) as shown in A. The damping (viscosity) of the oscillation increases as the sample coagulates until all is coagulated at which point the viscosity returns to baseline since the damping of the oscillation will not be affected anymore. This is followed by an increase in oscillation frequency (elasticity) when the platelets retract the clot. The height of the elasticity curve represents the strength of the clot. Variables detected are indicated with arrows (COT1- time to beginning of clot formation, COT2 – time to complete clot formation and Max elasticity (G'max) – maximum clot strength). B shows the differences in elasticity between FibScreen1 (full black line) and FibScreen2 (full grey line). The viscosity (COT1 and COT2) for FibScreen1 (dashed grey line) and FibScreen2 (dashed dotted line) is similar in a normal sample. Normal ranges are presented in the figure.