Skip to main content

Table 3 Observed DRPs

From: Drug - related emergency department visits by elderly patients presenting with non-specific complaints

Involved organ system Involved drugs
Electrolytes  
  Hyponatremia Thiazide diuretics (14), Non-thiazide diuretics (2), Anticonvulsants (2), Antidepressants± (2), ACE/ARB blockers (1)
  Hypokalemia Non-thiazide diuretics (3), Thiazide diuretics (1)
  Hyperkalemia ACE/ARB blockers (1)
Cardiovascular  
  Bradycardia Beta blockers (1)
  Hypotension Beta blockers (1)
  Acute heart failure NSAID (1)
  Hypovolemia/orthostatic dysregulation Thiazide diuretics (7), Non-thiazide diuretics (4),
Kidney  
  Hypovolemia, prerenal azotemia Non-thiazide diuretics (3), thiazide diuretics (1)
  Acute kidney injury ACE/ARB blockers (1), NSAID (3)
Coagulation system  
  Intracranial hemorrhage Vitamin-K antagonists (1)
Gastrointestinal  
  Nausea Opioids (1), Antibiotics (1), Interferon γ (1)
  Gastric ulcer/Gastritis NSAID (2)
Central nervous system  
  Aggravation of Parkinson’s Underdosing Anti-Parkinson drugs (1)
  Status epilepticus Malcompliance anticonvulsants (2)
Hematology  
  Neutropenic complication Chemotherapy (1)
  Anemia Underdosing of Darbepoetin alpha (1)
Endocrine  
  Diabetes mellitus Systemic steroids (1)
  Addison systemic steroids (1)
Other  
  Overdosing Opioids (7), Benzodiazepines (5), Anticonvulsants (3), Neuroleptics (1)
  Falls Neuroleptic (1)
  Tumor lysis syndrome Chemotherapy (1)
  Abusus Laxatives (1)
  1. In 7 cases, the DRP was caused by more than one drug class. In 2 cases, one drug caused more than one DRP.
  2. ±SSRI, SNRI, Tricyclic antidepressants.
  3. Vital signs within normal range at presentation.