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Table 1 Characteristics of included patients

From: Prognostic value of B-type natriuretic peptide (BNP) and its potential role in guiding fluid therapy in critically ill septic patients

Variables

Total (n = 67)

Alive (n = 40)

Dead (n = 27)

P value

Age (years)

59 ± 16

56 ± 15

64 ± 18

0.07

Sex (male, %)

43 (64.2)

25(62.5)

18 (66.7)

0.73

APACHEII

23 (19,31)

19 (16,23)

31 (25,38)

<0.01

Sources of infection (No. %)

0.47

  Lung

27 (40.3)

14 (35)

13 (48.2)

 

  Abdomen

10 (14.9)

5 (12.5)

5 (18.5)

 

  Urinary tract

15 (22.4)

11 (27.5)

4 (14.8)

 

  Blood stream

15 (22.4)

10 (25)

5 (18.5)

 

Mechanical ventilation (n, %)

31 (46.3)

16 (40)

15 (55.6)

0.21

Vasopressor use (n, %)

31 (46.3)

13 (32.5)

18 (66.7)

<0.01

Hemodynamic variables

  CVP (mmHg)

8 (6,13)

8 (6,13.5)

9 (6,12)

0.75

  CI (ml/m2)

3.5 ± 1.2

3.6 ± 1.1

3.3 ± 1.4

0.30

  SBP(mmHg)

130 ± 26

127 ± 24

135 ± 28

0.20

  DBP(mmHg)

66 ± 15

66 ± 16

65 ± 14

0.93

  HR (/min)

101 ± 21

104 ± 20

97 ± 23

0.23

  SI (ml/m2)

35 ± 12

35 ± 11

34 ± 14

0.76

  SVRI

1967 (1518,2573)

1850 (1466,2347)

2103 (1566,2917)

0.09

  EVLWI

11.0 ± 7.3

10.5 ± 6.6

11.8 ± 8.2

0.45

  GEDVI

746 (616,833)

744 (613,877)

751 (619,818)

0.55

Fluid balance (ml)

  Day 1

1432 (867,2133)

1003 (553,1827)

1890 (1432,2398)

<0.01

  Day 2

988 (210,1322)

499 (142,1003)

1234 (994,1332)

<0.01

  Day 3

324 (−324, 921)

391 (−183,1002)

122 (−1044,589)

0.16

  Total

2444 (1132,3652)

2051 (874,3201)

3086 (1643,4511)

0.03

BNP0 (pg/ml)

668 (457,818)

550 (331,768)

738 (596,937)

<0.01

BNP1 (pg/ml)

689 (534,889)

594 (446,732)

834 (701,1154)

<0.01

  1. BNP0 represents the B-type natriuretic peptide measured on ICU entry; BNP1 represents the BNP measured on day 3;
  2. Abbreviations: APACHEII,Acute Physiology and Chronic Health Evaluation; CVP, central venous pressure; CI, cardiac index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; SI, stroke volume; SVRI, systemic vascular resistance index; EVLWI, extravascular lung water; GEDVI, global end diastolic volume index; BNP, B-type natriuretic peptide.