Table 3 Relationship between MMP-9, c-Fn or fGCS and different clinical parameters
Parameters |  | Maximal MMP-9 between 6–12 hours | Maximal c-Fn between 24–48 hours | fGCS | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
|  |  | ng/ml | P | n | μg/ml | P | n | Score | P | n |
Oedema | No | 22.0 (11.8–51.5) | 0.24 | 22 | 6.0 (3.5–8.9) | 0.24 | 25 | 8.5 (4.0–12.0) | 0.007 | 26 |
|  | Yes | 31.0 (20.6–43.9) |  | 21 | 8.3 (3.9–11.2) |  | 21 | 4.0 (3.0–7.5) |  | 23 |
Midline shift (mm) | < 5 | 24.2 (15.8–55.2) | 0.52 | 29 | 6.6 (3.8–10.1) | 0.64 | 30 | 7.0 (4.0–10.0) | 0.28 | 33 |
|  | ≥ 5 | 25.9 (13.8–34.1) |  | 14 | 6.9 (3.6–10.2) |  | 16 | 4.0 (3.0–8.5) |  | 16 |
SAH | No | 20.8 (9.8–34.1) | 0.21 | 13 | 4.7 (3.0–9.2) | 0.26 | 12 | 10.0 (6.0–12.0) | 0.03 | 13 |
|  | Yes | 29.5 (16.3–53.8) |  | 30 | 7.2 (3.9–10.2) |  | 34 | 5.0 (3.0–8.5) |  | 36 |
IVH | No | 24.2 (13.8–53.8) | 0.71 | 33 | 7.6 (3.7–10.0) | 0.59 | 35 | 7.0 (3.0–10.0) | 0.99 | 37 |
|  | Yes | 25.9 (20.8–34.1) |  | 10 | 4.0 (3.9–8.9) |  | 11 | 5.5 (3.0–11.0) |  | 12 |
fGCS | 9-15 | 21.5 (11.8–28.9) | 0.13 | 13 | 4.6 (3.2–7.7) | 0.10 | 14 | 11.5 (10.0–14.5) | 0.000 | 16 |
|  | 3-8 | 30.5 (16.5–53.8) |  | 30 | 8.4 (3.9–10.7) |  | 32 | 4.0 (3.0–7.0) |  | 33 |
Pupil reaction on the field of the accident | Normal | 22.7 (12.8–47.7) | 0.74 | 20 | 4.7 (2.5–5.6) | 0.15 | 20 | 8.0 (4.0–12.5) | 0.07 | 24 |
|  | Abnormal | 27.2 (16.1–47.1) |  | 19 | 5.2 (2.7–7.3) |  | 19 | 4.0 (3.0–8.0) |  | 21 |
GCS14 | 9-15 | 21.6 (13.3–38.9) | 0.54 | 23 | 5.3 (3.8–8.9) | 0.16 | 25 | 7.5 (3.0–11.0) | 0.31 | 26 |
|  | 3-8 | 29.5 (16.1–52.7) |  | 20 | 8.3 (5.5–11.3) |  | 21 | 6.0 (3.0–8.0) |  | 23 |
GOSE at 3 months | 5-8 | 21.2 (15.3–61.1) | 0.72 | 4 | 4.7 (2.9–7.0) | 0.34 | 4 | 7.0 (3.3–10.5) | 0.94 | 4 |
|  | 1-4 | 28.9 (16.1–52.7) |  | 27 | 7.2 (3.3–10.1) |  | 30 | 7.0 (3.0–10.0) |  | 33 |
Mortality at 3 months | Alive | 21.6 (13.3–48.9) | 0.40 | 31 | 5.7 (3.5–9.6) | 0.11 | 33 | 7.0 (3.0–10.0) | 0.78 | 34 |
|  | Dead | 30.9 (19.6–44.3) |  | 12 | 8.3 (6.0–12.3) |  | 13 | 7.0 (3.0–8.5) |  | 15 |
LOS ≥ 10 days for survivors in ICU | No | 20.6 (9.8–31.0) | 0.14 | 17 | 4.0 (3.2–7.6) | 0.06 | 18 | 9.0 (5.5–11.5) | 0.02 | 19 |
|  | Yes | 27.2 (16.5–55.2) |  | 17 | 9.1 (3.7–10.7) |  | 16 | 5.0 (3.0–8.0) |  | 18 |
LOS ≥ 10 days or death in ICU | No | 20.6 (9.8–31.0) | 0.06 | 17 | 4.0 (3.2–7.6) | 0.007 | 18 | 9.0 (5.5–11.5) | 0.03 | 19 |
|  | Yes | 30.9 (18.6–53.8) |  | 26 | 8.9 (5.4–11.3) |  | 28 | 4.0 (3.0–8.0) |  | 30 |
LOS ≥ 17 days for survivors in acute hospital | No | 15.5 (6.9–26.7) | 0.04 | 16 | 3.9 (3.2–6.4) | 0.04 | 17 | 9.0 (7.0–12.0) | 0.01 | 18 |
|  | Yes | 27.2 (18.6–53.8) |  | 17 | 8.8 (4.0–10.1) |  | 17 | 3.0 (3.0–8.0) |  | 18 |