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Table 1 Ventilation characteristics at different compression:ventilation ratios, continuous chest compressions with asynchronous ventilation; and ventilation rates

From: Minute ventilation at different compression to ventilation ratios, different ventilation rates, and continuous chest compressions with asynchronous ventilation in a newborn manikin

Intervention Number of ventilations/min p-value* VT (ml) Absolute p-value* VT (ml) Per kg p-value* Mv (ml) p-value* Mv (ml) Per kg p-value* TI (s) p-value*
Continuous chest compressions with asynchronous ventilation 39 (39–39) <0.001 19.7 (18.8-21.1) 0.002 5.6 (5.4-6.0) 0.002 777 (735–836) <0.001 221 (210–239) <0.001 0.52 (0.49-0.58) 0.427
C:V = 3:1 120 events per minute 30 (29–30)   22.3 (21.9-23.8)   6.4 (6.3-6.8)   668 (642–697)   191 (183–199)   0.50 (0.48-0.55)  
C:V 9:3 120 events per minute 28 (28–30) 0.057 17.1 (16.5-17.1) <0.001 4.9 (4.8-5.1) <0.001 490 (468–506) <0.001 140 (134–144) 0.002 0.33 (0.33-0.34) <0.001
C:V 15:2 120 events per minute 14 (13–15) <0.001 19.1 (19.0-19.9) <0.001 5.5 (5.4-5.7) <0.001 268 (261–289) <0.001 77 (74–83) <0.001 0.33 (0.32-0.34) 0.001
Ventilations only 40 per minute 40 (40–40) <0.001 19.5 (18.8-19.9) <0.001 5.6 (5.4-5.7) <0.001 760 (734–775) <0.001 217 (210–221) <0.001 0.59 (0.57-0.71) 0.003
Ventilations only 60 per minute 58 (58–59) <0.001 17.4 (16.8-17.8) <0.001 5.0(4.8-5.1) <0.001 1013 (973–1028) <0.001 289 (278–294) <0.001 0.56 (0.53-0.60) 0.049
Ventilations only 120 per minute 118 (117–118) <0.001 13.1 (13.1-13.6) <0.001 3.8 (3.7-3.9) <0.001 1544 (1525–1595) <0.001 441 (436–456) <0.001 0.24 (0.24-0.25) <0.001
  1. Values are shown as median (IQR) *compared to a chest compression to ventilation ratio of 3:1.
  2. C:V = chest compressions to ventilations, VT = tidal volume, Mv = minute ventilation, TI = inspiratory time.