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Table 2 Comparison of laboratory data at ICU admission in overall population, insulin resistant patients, and non-insulin resistant patients

From: Early insulin resistance in severe trauma without head injury as outcome predictor? A prospective, monocentric pilot study

 

Overall

Insulin resistant patients

Non-insulin resistant patients

P

Number,% (N)

37

62.2% (23)

37.8% (14)

 

Leukocytes (n*1000/ml)

9.6 (7.9-13.1)

11.1 (9.1-3.7)

8.2 (7.8-9.5)

0.0301

Haemoglobin (gr/dl)

10.1 (9–11.4)

9.8 (9.2-11)

10.1 (9–11.9)

0.7441

Fibrinogen (mg/dl)

361 (317–525)

359 (313–527)

375 (345–490)

0.8413

Antithrombin III (%)

74 (64–87)

71 (65–86)

79 (62–88)

0.6885

d-dimersg/l)

3455 (2034–5960)

3655 (2591–5415)

3198 (1962–6387)

0.7398

Blood glucose (mmol/l)

7 (6.1-7.4)

7.2 (6.5-7.4)

6.3 (5.7-7.4)

0.1578

Plasma insulin (mU/l)

9.90 (4.78-19.48)

15.55 (11.10-24.08)

4.55 (3.23-5.48)

<0.0001

HOMA index

3.20 (1.46-5.76)

4.72 (3.65-8.84)

1.27 (0.983-1.57)

<0.0001

C-peptides (mmol/l)

0.72 (0.46-1.05)

0.95 (0.53-1.12)

0.43 (0.32-0.65)

0.0061

Glycated hemoglobin,%

5.4 (5.2-5.6)

5.5 (5.3-5.7)

5.4 (5.2-5.6)

0.2067

Total plasma proteins (g/dl)

4.80 (4.20-5.20)

4.7 (4.3-5.2)

4.8 (4.3-5.2)

0.9875

Plasma albumin (g/l)

25.70 (20.35-30.45)

25.7 (19.3-29.4)

26.1 (23.7-31.3)

0.4042

Arterial lactates (mmol/l)

1.15 (0.80-2)

1.2 (0.9-1.9)

1.3 (0.8-2)

0.8754

C-reactive protein (mg/l)

114 (74–165.5)

140.5 (90.8-197.8)

83 (70–97)

0.0265

Triglycerides (mg/dl)

77 (53–114)

88 (64–150)

57 (46–88)

0.2351

Total cholesterol (mg/dl)

106 (82–112)

108 (104–123)

83 (75–109)

0.0700

Cholesterol HDL (mg/dl)

26 (22–33)

26 (25–34)

24 (18–31)

0.2635

AST (U/l)

72 (35–165)

63 (38–169)

68 (34–155)

0.9388

ALT (U/l)

43 (28–122)

40 (28–69)

48 (30–154)

0.4659

CPK (U/l)

1556 (891–3531)

1336 (696–4228)

2040 (1149–3215)

0.5702

LDH (U/l)

537 (240–500)

297 (237–495)

391 (345–507)

0.1670

Myoglobin (ng/ml)

993 (340–1824)

762 (351–2475)

1316 (314–1574)

0.3185

  1. Continuous data are analysed with two-tail Student's t-test or Mann–Whitney test, as appropriate (D'Agostino & Pearson normality test). Continuous variables are expressed as medians with 25th to 75th interquartile range (IQR). P significant if <0.05 (bold).
  2. ALT alanine aminotransferase, AST aspartate aminotransferase, CPK creatine phosphokinase, HOMA Homeostasis Model Assessment, LDH lactate dehydrogenase, NT-pro-BNP N-terminal-pro-brain natriuretic peptide.