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Table 2 Comparison of laboratory data at ICU admission in overall population, insulin resistant patients, and non-insulin resistant patients

From: Early insulin resistance in severe trauma without head injury as outcome predictor? A prospective, monocentric pilot study

  Overall Insulin resistant patients Non-insulin resistant patients P
Number,% (N) 37 62.2% (23) 37.8% (14)  
Leukocytes (n*1000/ml) 9.6 (7.9-13.1) 11.1 (9.1-3.7) 8.2 (7.8-9.5) 0.0301
Haemoglobin (gr/dl) 10.1 (9–11.4) 9.8 (9.2-11) 10.1 (9–11.9) 0.7441
Fibrinogen (mg/dl) 361 (317–525) 359 (313–527) 375 (345–490) 0.8413
Antithrombin III (%) 74 (64–87) 71 (65–86) 79 (62–88) 0.6885
d-dimersg/l) 3455 (2034–5960) 3655 (2591–5415) 3198 (1962–6387) 0.7398
Blood glucose (mmol/l) 7 (6.1-7.4) 7.2 (6.5-7.4) 6.3 (5.7-7.4) 0.1578
Plasma insulin (mU/l) 9.90 (4.78-19.48) 15.55 (11.10-24.08) 4.55 (3.23-5.48) <0.0001
HOMA index 3.20 (1.46-5.76) 4.72 (3.65-8.84) 1.27 (0.983-1.57) <0.0001
C-peptides (mmol/l) 0.72 (0.46-1.05) 0.95 (0.53-1.12) 0.43 (0.32-0.65) 0.0061
Glycated hemoglobin,% 5.4 (5.2-5.6) 5.5 (5.3-5.7) 5.4 (5.2-5.6) 0.2067
Total plasma proteins (g/dl) 4.80 (4.20-5.20) 4.7 (4.3-5.2) 4.8 (4.3-5.2) 0.9875
Plasma albumin (g/l) 25.70 (20.35-30.45) 25.7 (19.3-29.4) 26.1 (23.7-31.3) 0.4042
Arterial lactates (mmol/l) 1.15 (0.80-2) 1.2 (0.9-1.9) 1.3 (0.8-2) 0.8754
C-reactive protein (mg/l) 114 (74–165.5) 140.5 (90.8-197.8) 83 (70–97) 0.0265
Triglycerides (mg/dl) 77 (53–114) 88 (64–150) 57 (46–88) 0.2351
Total cholesterol (mg/dl) 106 (82–112) 108 (104–123) 83 (75–109) 0.0700
Cholesterol HDL (mg/dl) 26 (22–33) 26 (25–34) 24 (18–31) 0.2635
AST (U/l) 72 (35–165) 63 (38–169) 68 (34–155) 0.9388
ALT (U/l) 43 (28–122) 40 (28–69) 48 (30–154) 0.4659
CPK (U/l) 1556 (891–3531) 1336 (696–4228) 2040 (1149–3215) 0.5702
LDH (U/l) 537 (240–500) 297 (237–495) 391 (345–507) 0.1670
Myoglobin (ng/ml) 993 (340–1824) 762 (351–2475) 1316 (314–1574) 0.3185
  1. Continuous data are analysed with two-tail Student's t-test or Mann–Whitney test, as appropriate (D'Agostino & Pearson normality test). Continuous variables are expressed as medians with 25th to 75th interquartile range (IQR). P significant if <0.05 (bold).
  2. ALT alanine aminotransferase, AST aspartate aminotransferase, CPK creatine phosphokinase, HOMA Homeostasis Model Assessment, LDH lactate dehydrogenase, NT-pro-BNP N-terminal-pro-brain natriuretic peptide.