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Table 1 Baseline characteristics for ICH patients with- and without early DNR order

From: Early do-not-resuscitate orders in intracerebral haemorrhage; frequency and predictive value for death and functional outcome. A retrospective cohort study

  Total Early DNR order No early DNR order P value(early DNR vs not)
n 197 80 (40.6) 117 (59.4)  
Men 88 (44.7) 31 (38.8) 57 (48.7)  
Women 109 (55.3) 49 (61.3) 60 (51.3) 0.190*
Age, mean ± SD 73 ± 14 78 ± 11 70 ± 14 <0.001
Hypertension medication 123 (62.4) 47 (58.8) 76 (65.5) 0.369
Current smoker 21 (10.7) 8 (10.4) 13 (11.3) 1.0
Atrial fibrillation 23 (11.7) 11 (13.8) 12 (10.3) 0.503
Former stroke 39 (19.8) 25 (31.3) 14 (12.1) 0.002
Diabetes 23 (11.7) 7 (8.8) 16 (13.7) 0.369
Warfarin 17 (9.0) 7 (9.5) 10 (8.8) 1.0
Haemorrhage site     
Lobar 81 (41.1) 31 (38.8) 50 (42.7)  
Deep 88 (44.7) 37 (46.3) 51 (43.6)  
Brainstem 11 (5.6) 4 (5.0) 7 (6.0)  
Cerebellar 16 (8.1) 7 (8.8) 9 (7.7)  
Multiple 1 (0.5) 1 (1.3) 0 (0) ns
Midlineshift 51 (25.9) 38 (47.5) 13 (11.1) <0.001
Intaventricular haemorrhage 66 (33.5) 45 (56.3) 21 (17.9) <0.001
Volume     
≤ 30 ml 146 (74.1) 99 (58.8) 47 (84.5)  
> 30 ml 51 (25.9) 18 (41.3) 33 (15.4) <0.001
Mean ± SD/
Median
26.5 ± 38.6/9.2 41.4 ± 47.1/22 16.4 ± 27.3/7 <0.001
Time from ICH to admission
< 2 hours 88 (44.9) 48 (41.0) 40 (50.6)  
2-24 hours 78 (39.8) 40 (42.7) 28 (35.4)  
> 24 hours 30 (15.3) 19 (16.2) 11 (13.9) 0.414
RLS on admission     
1 (alert) 99 (50.3) 19 (23.8) 80 (68.4)  
2-3 (drowsy) 63 (32.0) 39 (48.8) 24 (20.5)  
≥4 (unconscious) 35 (17.8) 22 (27.5) 13 (11.1) <0.001
Pre-ICH comorbidity 55 (27.9) 30 (37.5) 25(21.4) 0.01
Seizure 19 (9.6) 11 (13.8) 8 (6.8) 0.140
ICU care 18 (9.1) 9 (11.3) 9 (7.7) 0.454
Neurosurgery care 12 (6.1) 0 (0) 12 (10.3) 0.002
Prior DNR decision 3 (1.5) 2 (2.5) 1 (0.9) 0.568
  1. · women as compared to men.