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Table 2 Univariate and multivariate linear regression analysis of variables associated with sVEGFR1 in trauma patients upon admission to a Level I Trauma Centre

From: High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

  

Univariate

Multivariate (R2 = 0.38)

 

Unit

β (SE)

t-value

p-value

β (SE)

t-value

p-value

ISS

point

3.33 (0.95)

3.5

< 0.001

-1.38 (1.43)

-1.0

0.340

SBE

mmol/l

-13.8 (3.3)

-4.3

< 0.001

-7.9 (3.5)

-2.3

0.027

Adrenaline

ng/ml

34.7 (8.1)

4.3

< 0.001

20.1 (10.0)

2.0

0.048

hcDNA

%

1.97 (0.71)

2.8

0.007

0.12 (0.81)

0.1

0.886

IL-6

pg/ml

1.13 (0.21)

5.4

< 0.001

0.98 (0.29)

3.3

0.001

  1. Regression coefficients (β) with standard errors (SE), t- and p-values and R2 displayed for the multivariate model. P-values are shown in bold for variables with p < 0.05. Predicted change in sVEGFR1 (pg/ml) associated with one unit increase in injury severity score (ISS), SBE (mmol/l), circulating adrenaline (ng/ml), hcDNA (%) and IL-6 (pg/ml).