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Table 1 Contact criteria to discuss the need of ECMO

From: Feasibility of inter-hospital transportation using extra-corporeal membrane oxygenation (ECMO) support of patients affected by severe swine-flu(H1N1)-related ARDS


Acute respiratory failure with 1 of the following condition:


SaO2 < 85% for at least 1 hour


Oxygenation Index >25 for at least 6 hours after ventilation's optimisation


PaO2/FiO2 < 100 with PEEP ≥ 10cmH2O for at least 6 hours after ventilation's optimization


Hypercapnia with pH < 7.25


SvO2 < 65% with hematocrit > 30 and under vasoactive drugs infusion

  1. The Italian Ministry of Health dispositions for first contact criteria to discuss the need of ECMO in patients admitted to peripheral hospitals.
  2. The parameter are referred to a condition of lung protective ventilation's (tidal volume:4-6 ml/Kg of predicted body weight; plateau pressure ≤ 30 cmH20; PEEP >lower inflection point of the curve pressure-volume).
  3. PEEP: positive end-expiratory pressure; PaO2: arterial oxygen partial pressure; FiO2: inspired oxygen fraction; RR: respiratory rate; SaO2: peripheral oxygen saturation; Oxygenation Index: Mean airway pressure (cmH2O) * FiO2 * 100/PaO2; SvO2: central venous oxygen saturation.