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Table 2 Whole Blood Composition Compared with Component Therapy

From: The contemporary role of blood products and components used in trauma resuscitation

Whole Blood (500 mL) Component Therapy (660 mL)
Hematocrit 38-50% 1 unit PRBC = 335 mL with hematocrit 55%
Platelets 150-400 K/μL 1 unit platelets = 50 mL with 5.5 × 1010 platelets
Plasma Coagulation Factors = 100% 1 unit plasma = 275 mL with 80% of the coagulation activity compared with whole blood
  1. 1 unit PRBCs + 1 unit platelets + 1 unit FFP = 660 mL with hematocrit 29%, platelets 88 K/μL and coagulation activity 65% compared with whole blood. (Component volumes reported are based on data provided from a North American reference.)
  2. Reproduced with permission from Chest 2010; 137:209-220.