Time (hrs)
| |
0a
|
8
|
16
|
24
|
p-valueb
|
p-valuec
|
Overall p-value
|
---|
Na+
|
HH
|
139
|
148
|
153
|
151
|
<0.001
|
<0.001
|
<0.001
|
mmol/l
|
Control
|
139
|
141
|
141
|
142
|
0.001
| | |
Cl-
|
HH
|
100
|
116
|
125
|
121
|
<0.001
|
<0.001
|
<0.001
|
mmol/l
|
Control
|
100
|
107
|
109
|
110
|
<0.001
| | |
K+
|
HH
|
4.1
|
3.8
|
3.9
|
3.9
|
0.542
|
0.798
|
0.869
|
mmol/l
|
Control
|
4.1
|
4.2
|
4.0
|
3.8
|
0.343
| | |
Ca2+
|
HH
|
2.29
|
2.07
|
2.03
|
2.01
|
<0.001
|
0.689
|
<0.001
|
mmol/l
|
Control
|
2.29
|
2.14
|
2.01
|
2.04
|
<0.001
| | |
Hb
|
HH
|
15.1
|
13.8
|
13.0
|
12.1
|
<0.001
|
0.158
|
<0.001
|
g/dl
|
Control
|
15.1
|
14.6
|
13.8
|
13.0
|
<0.001
| | |
Hematocrit
|
HH
|
0.45
|
0.41
|
0.39
|
0.36
|
<0.001
|
0.183
|
<0.001
|
|
Control
|
0.45
|
0.44
|
0.40
|
0.39
|
<0.001
| | |
pH
|
HH
|
7.28
|
7.29
|
7.31
|
7.33
|
0.098
|
0.253
|
0.043
|
|
Control
|
7.28
|
7.35
|
7.34
|
7.37
|
0.002
| | |
Osmolality
|
HH
|
311
|
320
|
319
|
318
|
0.015
|
<0.001
|
<0.001
|
mosm/kg
|
Control
|
311
|
302
|
299
|
299
|
<0.001
| | |
- a Estimates based on mixed effects model, with no baseline differences assumed.
- b Contrast from baseline at 24 hours
- c Contrast between groups at 24 hours