Box plots of total serum amyloid A (SAA) levels in healthy volunteers and ORP maxima plasma samples of multi-trauma patients. For both multi-trauma groups, total SAA levels were measured in plasma samples that recorded the maximum ORP value. Outliers (i.e. ± 2 standard deviations) for each group are labeled with a plus sign (+). Total SAA levels were calculated by adding the area under the curve (AUC) for the 6 major species of SAA (see Figure 2). Statistical significance (p < 0.05) versus the control group is indicated with an asterisk (*).