Table 3 Studies evaluating VHA in trauma patients

Kaufman (1997)

69

13/29

RS

Moderately injured patients (ISS 13) were hypercoagulable whereas severely injured (ISS 29) patients were hypocoagulable according to VHA

[51]

Schreiber (2005)

65

23

RS

62% of the patients where hypercoagulable 1^st day of trauma according to VHA which is more sensitive to identify this state than RCoT.

[52]

Rugeri (2007)

90

22

PO

VHA rapidly detects systemic changes of in vivo coagulation in trauma patients, and it might be a helpful device in guiding transfusion.

[76]

Plotkin (2008)

44

21

RS

VHA is a more accurate indicator of transfusion requirements than PT, APTT and INR

[77]

Levrat (2008)

87

20/75

PO

VHA provides rapid and accurate detection of hyperfibrinolysis in severely injured trauma patients

[78]

Schöchl (2009)

33

47

PO

VHA based diagnosis of hyperfibrinolysis predicted outcome in severely injured trauma patients

[79]

Carroll (2009)

161

20

PO

Abnormal VHA parameters correlated with fatality. Coagulopathy as evaluated by VHA was present already on the scene of accident.

[80]

Jaeger (2009)

20

??

RS

RapidTEG provides earlier detection of coagulopathy than standard VHA and RCoT

[81]

Park (2009)

78

20

PO

VHA detected hypercoagulability and this was not seen with RCoT in trauma patients

[82]

Kashuk (2009)

44

29

RS

RapidTEG may effectively guide transfusion therapy in trauma patients

[83]