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Table 3 Studies evaluating VHA in trauma patients

From: Thrombelastography and tromboelastometry in assessing coagulopathy in trauma

Author No. ISS Study type Major conclusions Ref.
Kaufman (1997) 69 13/29 RS Moderately injured patients (ISS 13) were hypercoagulable whereas severely injured (ISS 29) patients were hypocoagulable according to VHA [51]
Schreiber (2005) 65 23 RS 62% of the patients where hypercoagulable 1st day of trauma according to VHA which is more sensitive to identify this state than RCoT. [52]
Rugeri (2007) 90 22 PO VHA rapidly detects systemic changes of in vivo coagulation in trauma patients, and it might be a helpful device in guiding transfusion. [76]
Plotkin (2008) 44 21 RS VHA is a more accurate indicator of transfusion requirements than PT, APTT and INR [77]
Levrat (2008) 87 20/75 PO VHA provides rapid and accurate detection of hyperfibrinolysis in severely injured trauma patients [78]
Schöchl (2009) 33 47 PO VHA based diagnosis of hyperfibrinolysis predicted outcome in severely injured trauma patients [79]
Carroll (2009) 161 20 PO Abnormal VHA parameters correlated with fatality. Coagulopathy as evaluated by VHA was present already on the scene of accident. [80]
Jaeger (2009) 20 ?? RS RapidTEG provides earlier detection of coagulopathy than standard VHA and RCoT [81]
Park (2009) 78 20 PO VHA detected hypercoagulability and this was not seen with RCoT in trauma patients [82]
Kashuk (2009) 44 29 RS RapidTEG may effectively guide transfusion therapy in trauma patients [83]
  1. RCoT = routine coagulation tests, RS = Retrospective study, PO = Prospective observational study