From: Acute lung injury and the acute respiratory distress syndrome in the injured patient
Proven benefit | Suggested benefit in select patients | Indeterminate benefit | Suggested as not harmful | No benefit |
---|---|---|---|---|
Low tidal volumes of 6 ml/kg predicted body weight | Fluid restriction | Recruitment maneuvers | Higher PEEP | Surfactant |
PEEP ≥ 5 cm H2O | Incentive spirometry | High-frequency oscillatory ventilation |  | Prostaglandin E1 |
Plateau pressures ≤ 30 cm H2O | Patient-initiated positive airway pressure therapy | Airway pressure release ventilation |  | N-acetylcysteine |
 | Non-invasive positive pressure ventilation | Steroids |  |  |
 | Early use of neuromuscular blocking agents |  |  |  |
 | Extracorporeal membrane oxygenation |  |  |  |
 | Rib fracture fixation |  |  |  |
 | Prone positioning |  |  |  |